Penn State Health Medical Group - Nyes Road Specialties is a medical clinic in Harrisburg, PA, located at 121 Nyes Rd C. It holds a rating of 3.40 based on 56 reviews. The clinic provides specialized medical care including audiology, certified nurse midwifery, colon and rectal surgery, dermatology, gastroenterology, nephrology, neurological surgery, nurse practitioner services, obstetrics and gynecology, otolaryngology-head and neck surgery, pediatric dermatology, physician assistant services, spine surgery, and transplant hepatology. Patients can contact the office at 717-657-4045 or fax inquiries to 717-531-0405.
As part of the Penn State Health integrated academic health system, this clinic connects to a network serving 15 counties in central Pennsylvania. The system includes nearly 200 outpatient practices, five adult acute care hospitals, a rehabilitation hospital, and a children’s hospital. Penn State Health Milton S. Hershey Medical Center serves as the primary academic medical center, partnering with the Penn State College of Medicine to advance research and education.
The health system has earned recognition from U.S. News & World Report, including being named one of the top hospitals in the nation for 2025-2026 and ranked No. 1 in the Harrisburg metro region. Penn State Health hospitals have received Comprehensive Stroke Center designation from The Joint Commission and the American Heart Association/American Stroke Association. Recognitions include Stroke Gold Plus, Heart Failure Gold Plus, and Target: Type 2 Diabetes Honor Roll designations. The system also provides free medical interpretation in more than 150 languages and dialects, including American Sign Language.
Penn State Health Medical Group - Nyes Road Specialties delivers specialized medical services to the Harrisburg community.
The clinic sits on Nyes Road C in Harrisburg, PA, just 0.1 miles from Nyes Road and Jonestown Road. It is located within 0.2 miles of Thomas B. George park and near Paxtonia Elementary School.
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